Program 2007

Thursday, February 8^th, 2007

14.00 – 15.00 Arrival and registration

15.00 – 15.10 Welcome

                        J. Michael Hasenkam, President of SSRCTS

Chairman: Vibeke Hjortdal

15.15 – 15.30

Optimization of an Experimental Porcine Model for Valvular Aortic Stenosis. (1)

M. Sørensen, H. Jensen, J. M. Hasenkam, E. Sloth - (Aarhus, Denmark) 

           15.30 – 15.45

Substitution of Potassium with Adenosine in Cold Crystalloid Cardioplegic Solution improves Cardioprotection. (2)

Ø. Jakobsen, S. Muller, E. Aarsæther, D.G. Sørlie - (Tromsø, Norway)

15.45 – 16.00

The cardioprotective effect of adenosine pretreatment may be masked when it is combined with blood cardioplegia. (3)

A. Shalaby, O. Järvinen, J. Laurikka, H. Porkkala, T. Rinne, M. Tarkka - (Finland)

16.00 – 16.15

Progressive Deterioration of Left Ventricular Function in Type-2 Diabetic mice: In-Vivo Evaluation by Conductance Catheter Technique. (4)

J. M. Nielsen, S.B. Kristiansen, T.T. Nielsen, H.E. Bøtker - (Aarhus, Denmark)

16.15 – 16.30

The role of VAP-1 in acute lung injury. (5)
J. Kiss,  M. Salmi, T. Savunen, S. Jalkanen -  (Turku, Finland)

16.30 - 16.45

Effects of pH Management During Selective Antegrade Cerebral Perfusion on Cerebral Microcirculation and Metabolism: Alpha-Stat Versus pH-Stat. (6)

S. Dahlbacka, J. Mäkelä, H. Alaoja, E. Niemelä, P. Laurila,  K.Kiviluoma,  A. Honkanen,  P. Ohtonen, V. Anttila, and T. Juvonen -  (Oulu, Finland)

17.15 – 18.15 POSTER SESSION I

Chairman: Leidulf Segadal

101

Long Term Survival After Coronary Endarterectomy In Patients Undergoing

Combined Coronary And Valvular Surgery – A Fifteen Year Experience.

S.Kumar, S.Agarwala, C.Talbot, U. R. Nair -  (Leeds, UK)

102
Does perfusion precondition the heart: A word of caution.
A.   Rutkovskiy, K.-O. Stensløkken M.-L. Kaljusto, M.B. Dahl, J. Vaage  - (Oslo, Norway)
 

103

Programmed cell death (apoptosis) in ischemia-reperfusion injury caused by open heart surgery.

M. Malmberg, J. Pärkkä , Tommi Vähäsilta, A. Saraste, J. Kiss,  E. Kentala,  T. Savunen - (Turku, Finland)

104

An animal model of chronic ischemic mitral regurgitation.

M. Bjerre,  H. Jensen , J. Dahl Andersen, S.Ringgaard, Y. Kim, M. Smerup, P. Wierup, J. M. Hasenkam, S. Lyager Nielsen  - (Aarhus, Denmark)

105

Challenging the 12 hour limit for primary angioplasty in ST-Elevation Myocardial Infarction: Myocardial Salvage in Patients with Symptoms for 12-72 Hours.

M. Busk, M. Böttcher, S. S. Nielsen, A. Kaltoft, M. Rehling, T. T. Nielsen, S. D. Kristensen  - (Aarhus, Denmark)

106

Effect of hypothermic cardiopulmonary bypass on intraperitoneal lactate, pyruvate and glycerol in patients undergoing CABG – measurement using microdialysis.

R. K. P. Adluri, A. V. Singh, M. Baker, J. Skoyles, I. M. Mitchell -  (Nottingham, UK)

107

Mechanical heart valve cavitation in patients with bileaflet valves.

P. Johansen, T. S. Andersen, J. M. Hasenkam, H. Nygaard, P.K. Paulsen -  (Aarhus, Denmark)

108

Does Histology Accurately Predict the Clinical Behaviour of Bronchopulmonary Carcinoids? - Results From an Icelandic Population-Based Study.

J.M.Sigurdardottir, K.B. Johannsson, H. Isaksson, S. Jonsson, B. Torfason, T. Gudbjartsson -  (Reykjavik, Iceland)

109

Effects of PDE₅-inhibition by sildenafil in the pressure overloaded right heart.

A. Andersen, J.E. Nielsen-Kudsk, J.M. Nielsen, U.K. Skov, C.D. Peters, E. Sloth - (Aarhus, Denmark)

110

Assessment of the immunologic response against decellularized porcine mitral valve tissue in a mouse model.

 H. Waziri, J. M. Nielsen, M. Smerup, E. Falk, J. M. Hasenkam - (Aarhus, Denmark)

111

Contracting cardiomyocytes and endothelial cells generated from mouse embryonic stem cells show immunofluorescence activation of the TGF-β pathway.

S. J. Oddsson, E. Steingrimsson, G. Valdimarsdottir  - (Reykjavik, Iceland)

112

Assessment of hemodynamic conditions in a-v fistulas with MRI  and computational fluid dynamics.

A. K. Niemann, S. Ringgaard, E. T. Fründ, S. A. Kock, S. E. Petersen J. M. Hasenkam - (Aarhus, Denmark) 

18.15 – 18.30 Coffee break 

      18.30 – 20.00 ORAL SESSION II

Chairman: Jarle Vaage

18.30- 18.45

18.45 – 19.00

Deep Sternal Wound Infections Following Open Heart Surgery in Iceland 1997-2004. (8)

S. Steingrimsson, M. Gottfredsson, B.Torfason, K.G. Kristinsson,  T. Gudbjartsson - (Reykjavik, Iceland)

19.00 – 19.15

Minimally invasive aortic replacement with minimal risk to the patients is a result of experimental surgery and ongoing technical improvements. (9)

S. Foghsgaard, H.K. Kjaergard  - (Gentofte, Denmark)

         19.15 – 19.30

Microalbuminuria is associated with longer ICU stay and higher mortality in patients undergoing cardiac surgery. (10)

M.M. Mikkelsen,  N.H.Andersen, T.D.Christensen, S.P. Johnsen, J.Gjedsted, T.K.Hansen, C.E. Mogensen, H. Eiskjær H, V.E.Hjortdal -  (Aarhus, Denmark)

19.30 – 19.45

Fibrinogen: A Potential Biomarker For Bleeding And Blood Transfusion After Cardiac Surgery. (11)

M. Karlsson, M. Hyllner, A. Jeppsson  ^_ (Gothenburg, Sweden)

19.45 – 20.00

Comparison of Video-Assisted Thoracoscopic Surgery and Limited Axillary Thoracotomy for Spontaneous Pneumothorax. (12)

G.F. Tomasdottir, B. Torfason, H. Isaksson , T. Gudbjartsson  - (Reykjavik, Iceland)

Friday, February 9^th, 2007

14.00 – 15.00 ORAL SESSION III

Chairman: J. Michael Hasenkam  

14.00 – 14.15

            Epicardial Cryoablation of Atrial Fibrillation: Initial Results on A Curative Therapy. (13)

L.F. López Almodóvar, A. Cañas, J. Buendía, P. Lima. - (Toledo, Spain)

14.15 – 14.30

Intramyocardial Versus Intracoronary Stem Cell Transplantation Method, In Vivo SPECT Imaging. (14)

J. Mäkelä, J.Rimpiläinen, K.Ylitalo, S.Lehtonen, H.Alaoja, E.Niemelä, J.Heikkilä, S. Dahlbacka, T.Mäkikallio, K. Kiviluoma, T.Paavonen, T.Juvonen, V.Anttila, P. Lehenkari - (Oulu, Finland)
 

14.30 – 14.45 
Interaction between the sodium-calcium exchanger and phosphokinases in postconditioning. (15)
A. Rutkovskiy, M.-L. Kaljusto, K.-O. Stensløkken, M.B.Dahl, J.Vaage  - (Oslo, Norway)

14.45 – 15.00
Extra-corporeal circulation optimization (ECCO) system during cardiopulmonary bypass. (16)
T. Vähäsilta, M. Valtonen, T. Kaila-Keinänen, K.Kuttila -  (Turku, Finland)

15.00 – 15.15 Coffee break

Chairman: Timo Savunen

113

Recombinant FVIIa therapy of major bleedings in cardiac surgery in Iceland.

J.P. Ingimarsson,  F. Valsson, B. Vidarsson, P.T. Onundarson , B. Torfason, T. Gudbjartsson  ^_ (Reykjavik, Iceland)

114
Congenital diaphragmatic hernia:  Improved surgical results should influence abortion decision making.

T. Gudbjartsson, C.Z. Topan,  L.T.Larsson, A. Gunnarsdottir, Th. Rosmundsson, A. Dagbjartsson  - (Reykjavik, Iceland)

115

Force Balance in the Mitral Valve Annulus: New Results from Novel Modalities and Measurement Techniques.

M. O. Jensen, H. Jensen, S.Lyager Nielsen, M. Smerup, P. Johansen, A. P. Yoganathan,  H. Nygaard, J. M. Hasenkam  - (Aarhus, Denmark)

         116

Papillary muscle relocation in addition to down-sized ring annuloplasty  improves mitral valve coaptation geometry in chronic functional ischemic mitral valve regurgitation.

H. Jensen, M. Smerup, M.Ølgaard, M. Bjerre, J. D. Andersen, E. Sloth, W.Yong Kim, S. Ringgaard, M. Hasenkam, S. Lyager Nielsen - (Aarhus, Denmark)

117

Coronary Artery Bypass Grafting With Arterial Revascularization

A randomized trial comparing LIMA and vein grafts versus

total arterial revascularization for coronary artery bypass grafting.

            S. Damgaard, J.T. Lund, N.B. Lilleør, M.Perko, K.S. Jensen, B. Dimo, M.B. Jensen, J.K.Madsen & D.A. Steinbrüchel - (Copenhagen, Denmark)

          118
          Technical Approach to Acute Neonatal Piglet Single-Ventricle Physiology Model

C. E. Ionan, D.Hua, D.Wilson, C. Woolard, E.H. Austin  - (Detroit, USA)

119

Nitric oxide synthesis in human umbilical vein endothelial cell culture is stimulated by histamine and thrombine.

H. Sigurjónsson, B. Thors, H. Halldórsson, G. Þorgeirsson  - (Reykjavik, Iceland)

120

Cardiac Diffusion Tensor Magnetic Resonance Imaging for Evaluation of Right Ventricular Hypertrophy.

E.A. Nielsen, M. Smerup, S. Ringgaard, M. Pedersen, P. Vestergaard-Poulsen, J. Frandsen, J.R. Nyengaard, and V. Hjortdal  - (Aarhus, Denmark) 

121

Intraoperative insulin resistance during coronary surgery in diabetic and non-diabetic patients-parallel microdialysis and organ balance technique studying skeletal muscle and fat tissue (preliminary results).

Z. Szabó  - (Linköping, Sweden)

122

Cavoatrial Extension of Childhood Renal Tumours:  A Single Institution 20 -Year Case Series.

D.V.T. Harischandra, R.K. Firmin, G.J. Peek, K. Yadav, R. J. Stewart  - (Leicester, UK)

          123

Platelets Damage Causes Immunosuppression Following Cardiopulmonary Bypass.

S. Attaran, J. Hutchinson, A. El-Gamel  - (London, UK)

          124

Tissue Cardiomyoplasty Using Cell-Seeded Biodegradable Nanopolymerized Scaffold to Repair Damaged Myocardium: An Ovine Model.

H. Ahmadi, M. Soleimani , E. Fayazzadeh , S. Rabbani, N. Ahmadbeigi, Y. Mohammadi - (Tehran, Iran) 

         16.15 – 16.45 Coffee break

MAIN TOPIC - Animal Models in Cardiovascular Research

Chairman: Guro Valen, Truls Myrmel

16.45 – 17.15   

The undivided reptile heart: An adaptation to low metabolic rate or an atavistic relict?

Tobias Wang, Aarhus University, Denmark 

17.15 – 17.40    
Rodent models of human disease
Guro Valen, Oslo, Norway 

17.40 – 18.05    
A pig is more human than the mouse. Hemodynamics, genetics
molecular biology
Truls Myrmel, Tromsoe, Norway

18.05 – 18.20 Coffee break

18.20 – 18.45   
Surviving pig model in experimental cardiothoracic research
Personal experience
Tatu Juvonen, Oulu, Finland 

18.45 – 19.05   
A heart that beats without oxygen
Kåre-Olav Stensløkken

19.05 – 19.30   
Discussion  

19.30 – 20.00 
Beer and Business
Announcement of Presenters Awards

Dinner (buffet)

Saturday, February 10th, 2007

14.00 – 14.40 ORAL SESSION IV

Chairman: Anders Jeppsson 

14.00 – 14.15
Single-Stage Repair of Coarctation of the Aorta with 
Hypoplastic Aortic Arch Associated with Ventricular Septal Defect. 
Application for Extended End-to-Side Anastomosis and Antegrade 
Cerebral Perfusion during Hypothermic Circulatory Arrest. (17)
C. E. Ionan,  H.L. Walters, and R.E. Delius - (Detroit, USA)

14.15 – 14.30

Myocardial Protection Evoked By Hyperoxic Exposure Involves Signaling Through Nitric Oxide and Mitogen Activated Protein Kinases. (18)

A. Ruusalepp, G. Czibik, T. Flatebø, J. Vaage, G. Valen  - (Tartu, Estonia/ Oslo, Norway)

14.30 – 14.45

Hemodynamic effects of the intracoronary administration of urocortin 2 in the anesthetized pig. (19)

E. Grossini, PP Caimmi, C Molinari, G Teodori, G. Vacca -  (Novara, Italy)
 

14.45 – 15.00
Does continuous sevoflurane inhalation modify infarct size in vivo in a porcine closed-chest ischemia-reperfusion model? (20)
J. Rolighed Larsen, S. Aagaard, J.M. Hasenkam, R.H. Lie, E. Sloth -  (Aarhus, Denmark)

          15.00 – 15.15 Coffee break

POSTGRADUATE COURSE  Tricuspid Valve Surgery

15.15 – 16.00
Tricuspid valve repair, when and how?
Mati Lepojärvi, Finland

16.00 – 16.30 Coffee break

16. 30 – 19.00 WET LAB
Practical exercises on ex vivo pig hearts with main emphasis on 
tricuspid valve surgery  

19.00  Adjourn the meeting

Presidential dinner and pompous speeches